A review of various studies of the effectiveness of CBD in the treatment of anxiety.

It establishes a sense of relaxation, which reduces thoughts of stress and anxiety. While there is no “remedy” for anxiety, Cannabidiol CBD oil can assist you with controlling it symptoms. Some people with depression issues use it as a permanent therapy while others only take it as needed.

Look at preliminary report from British Association for Psychopharmacology “Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder”.

Animal and human studies indicate that cannabidiol (CBD), a major constituent of cannabis, has anxiolytic properties. However, no study to date has investigated the effects of this compound on human pathological anxiety and its underlying brain mechanisms. The aim of the present study was to investigate this in patients with generalized social anxiety disorder (SAD) using functional neuroimaging.

The findings reported herein need to be interpreted with caution, given the limitations of the study. First, it would have been desirable to measure plasma levels of CBD and relate such measurements to the magnitude of rCBF changes; without a dose-response curve, there remain doubts about the regional cerebral effects of CBD. However, it should be pointed out that previous investigations have not been able to confirm whether there is a direct relationship between plasma levels of cannabinoids, in particular CBD, and their clinical effects (Agurell et al., 1986). In addition, the subject sample was small and without a sample of control subjects, and the relatively lower sensitivity of the SPECT technique compared with other functional imaging methods limited the statistical power of the study. Also, given the intrinsically limited spatial resolution of SPECT and the smoothing stage included in the SPM processing before the statistical analysis, caution is warranted in the interpretation of findings of large foci of tracer uptake changes in small brain structures(such as the amygdala, hippocampus and parahippocampalgyrus).

In conclusion, our results support the notion that CBD has anxiolytic effects that are associated with an action on limbic and paralimbic areas of the brain. This suggests a potential usefulness of CBD in ameliorating symptoms of clinically significant anxiety.  Since CBD has important advantages in comparison with the currently available pharmacological agents for the treatment of SAD, such as an early onset of action and lack of important side effects, this compound may be a promising novel therapeutic in the management of generalized SAD. However, double-blind, placebo-controlled long-term studies would be necessary to further confirm these observations.

 In the article “Cannabidiol (CBD) — what we know and what we don’t” Doctor Peter Grinspoon, MD From Harvard University wrote:

Cannabidiol (CBD) has been recently covered in the media, and you may have even seen it as an add-in booster to your post-workout smoothie or morning coffee. What exactly is CBD? Why is it suddenly so popular?

The evidence for cannabidiol health benefits

CBD has been touted for a wide variety of health issues, but the strongest scientific evidence is for its effectiveness in treating some of the cruelest childhood epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure medications. In numerous studies, CBD was able to reduce the number of seizures, and in some cases it was able to stop them altogether. Videos of the effects of CBD on these children and their seizures are readily available on the Internet for viewing, and they are quite striking. Recently the FDA approved the first ever cannabis-derived medicine for these conditions, Epidiolex, which contains CBD.

CBD is commonly used to address anxiety, and for patients who suffer through the misery of insomnia, studies suggest that CBD may help with both falling asleep and staying asleep.

CBD may offer an option for treating different types of chronic pain. A study from the European Journal of Pain showed, using an animal model, CBD applied on the skin could help lower pain and inflammation due to arthritis. Another study demonstrated the mechanism by which CBD inhibits inflammatory and neuropathic pain, two of the most difficult types of chronic pain to treat. More study in humans is needed in this area to substantiate the claims of CBD proponents about pain control.

01/04/2020 stopanxiety

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